AP BIOLOGY

THE HUMAN IMMUNE SYSTEM

AIDS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The immunoblot detected gp120 protein in the blood serum. This protein is typical for the following disease:
A
Tuberculosis.
B
Poliomyelitis.
C
Syphilis.
D
HIV
E
Virus B hepatitis.
Explanation: 

Detailed explanation-1: -The gp120 molecule of HIV-1 is a glycoprotein that is part of the outer layer of the virus. It presents itself as viral membrane spikes consisting of 3 molecules of gp120 linked together and anchored to the membrane by gp41 protein.

Detailed explanation-2: -HIV GP120 protein (or gp120) is the name of the glycoprotein which forms the spikes sticking out of a HIV virus particle. HIV gp120 protein is essential for virus entry into cells as it plays a vital role in seeking out specific cell surface receptors for entry.

Detailed explanation-3: -Env extends from the surface of the HIV virus particle. The spike-shaped protein is “trimeric”-with 3 identical molecules, each with a cap-like region called glycoprotein 120 (gp120) and a stem called glycoprotein 41 (gp41) that anchors Env in the viral membrane.

Detailed explanation-4: -HIV has a particular affinity for the T4 helper lymphocytes and the gp120 envelope glycoprotein of HIV specifically binds to the CD4 molecule receptor site on the surface of the helper lymphocyte.

There is 1 question to complete.