AP BIOLOGY

THE HUMAN IMMUNE SYSTEM

BLOOD GROUPS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
If a person with Type B blood receives a transfusion of Type O blood, what will result?
A
Agglutination of the donors blood
B
Agglutination of the recipients blood
C
Agglutination of both the bloods
D
No agglutination
Explanation: 

Detailed explanation-1: -For example, if someone with Type O blood (blood with no A or B antigens on the surface of red blood cells) received red blood cells donated from someone with Type B blood (blood containing B antigens), the recipient’s immune system would immediately identify the new blood cells as foreign and seek to destroy them.

Detailed explanation-2: -In the United States, the most common blood type is O, followed closely by type A. If you have type O blood, you can only get type O red blood cell transfusions. But you can give your red blood cells to people with type A, B, AB, or O blood, which is why you are sometimes called a universal donor.

Detailed explanation-3: -Type O patients have naturally occurring anti-A and anti-B antibodies in their blood. A type O patient would immediately react to the type A or type B blood being transfused into them. The ABO system is very antigenic and this transfusion would cause a very strong immune response. This response could be fatal.

Detailed explanation-4: -Whereas, a type O blood sample will not agglutinate with either type A or type B antibodies as type O blood contains no antigens.

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