THE HUMAN IMMUNE SYSTEM
BLOOD GROUPS
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
Fy(a+b-)
|
|
Fy(a-b+)
|
|
Fy(a+b+)
|
|
Fy(a-b-)
|
Detailed explanation-1: -The null phenotype Fy(a-b-) was the most prevalent among this population. This study highlights the importance of investigating FY alleles in different provinces of the Kingdom of Saudi Arabia.
Detailed explanation-2: -Four major Duffy phenotypes:-Fy(a+b-), Fy(a+b+), Fy(a-b+), Fy(a-b-): The Fya and Fyb antigens are found commonly in Europeans (Fya 66% and Fyb 83%) and Asians (Fya 99% and Fyb18. 5%), while less common in Africans (Fya 10% and Fyb 23%).
Detailed explanation-3: -The Duffy system is defined by three alleles: FY*A and FY*B encode two antithetical antigens, Fya and Fyb and FY*0 (FY null) is the major allele in Africans and occurs rarely in other populations.
Detailed explanation-4: -In a gene pool there are many different alleles that a species can have. When many alleles exist for the same gene, the most common phenotype or genotype among a population is denoted as the wild-type. It is often abbreviated, in genetic shorthand, as “+”. Wild-type is considered the standard or norm.