AP BIOLOGY

THE HUMAN IMMUNE SYSTEM

BLOOD GROUPS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the most frequent Duffy phenotype in the middle east?
A
Fy(a+b-)
B
Fy(a-b+)
C
Fy(a+b+)
D
Fy(a-b-)
Explanation: 

Detailed explanation-1: -The null phenotype Fy(a-b-) was the most prevalent among this population. This study highlights the importance of investigating FY alleles in different provinces of the Kingdom of Saudi Arabia.

Detailed explanation-2: -Four major Duffy phenotypes:-Fy(a+b-), Fy(a+b+), Fy(a-b+), Fy(a-b-): The Fya and Fyb antigens are found commonly in Europeans (Fya 66% and Fyb 83%) and Asians (Fya 99% and Fyb18. 5%), while less common in Africans (Fya 10% and Fyb 23%).

Detailed explanation-3: -The Duffy system is defined by three alleles: FY*A and FY*B encode two antithetical antigens, Fya and Fyb and FY*0 (FY null) is the major allele in Africans and occurs rarely in other populations.

Detailed explanation-4: -In a gene pool there are many different alleles that a species can have. When many alleles exist for the same gene, the most common phenotype or genotype among a population is denoted as the wild-type. It is often abbreviated, in genetic shorthand, as “+”. Wild-type is considered the standard or norm.

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