AP BIOLOGY

Detailed explanation-1: -Precursors of T cells migrate from the bone marrow and mature in the thymus. This process is similar to that for B cells, including the sequential rearrangement of antigen receptor gene segments.

Detailed explanation-2: -These cells may be protective against autoimmunity. The remaining cells exit the thymus as mature naive T cells. This process is an important component of central tolerance, a process that prevents the formation of self-reactive T cells that are capable of inducing autoimmune diseases in the host.

Detailed explanation-3: -T lymphocytes originate from bone marrow progenitors that migrate to the thymus for maturation, selection, and subsequent export to the periphery.

Detailed explanation-4: -The primary function of the thymus gland is to train special white blood cells called T-lymphocytes or T-cells. White blood cells (lymphocytes) travel from your bone marrow to your thymus. The lymphocytes mature and become specialized T-cells in your thymus. After the T-cells have matured, they enter your bloodstream.

Detailed explanation-5: -T-cells mature in the thymus gland or in the lymph nodes. Since the thymus is only 10-15% functional in the adult, the lymph nodes take on greater importance in the maturation process.