AP BIOLOGY

Detailed explanation-1: -The inflammatory response (inflammation) occurs when tissues are injured by bacteria, trauma, toxins, heat, or any other cause. The damaged cells release chemicals including histamine, bradykinin, and prostaglandins. These chemicals cause blood vessels to leak fluid into the tissues, causing swelling.

Detailed explanation-2: -One of the best-known chemical mediators released from cells during inflammation is histamine, which triggers vasodilation and increases vascular permeability. Stored in granules of circulating basophils and mast cells, histamine is released immediately when these cells are injured.

Detailed explanation-3: -Vasoactive Amines Histamine is more important than serotonin in humans; it acts mainly on venules that have H1-histamine receptors. Both of these amines cause vasodilation and increased permeability and are probably the main agents responsible for the immediate phase of the acute inflammatory response.

Detailed explanation-4: -Your immune system sends out its first responders: inflammatory cells and cytokines (substances that stimulate more inflammatory cells). These cells begin an inflammatory response to trap bacteria and other offending agents or start healing injured tissue. The result can be pain, swelling, bruising or redness.