THE HUMAN IMMUNE SYSTEM
IMMUNE RESPONSE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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It divides by mitosis producing a clone of cells.
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It begins transcription and produces antigens.
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It differentiates into memory cells.
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It produces antibodies using its extensive rough endoplasmic reticulum (rER).
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Detailed explanation-1: -B lymphocyte activation is initiated by the binding of antigens to the clonally expressed B cell receptors (BCRs) triggering signaling cascades that lead to the transcription of a variety of genes associated with B cell activation.
Detailed explanation-2: -Interaction with antigens causes B cells to multiply into clones of immunoglobulin-secreting cells. Then the B cells are stimulated by various cytokines to develop into the antibody-producing cells called plasma cells.
Detailed explanation-3: -Each B cell produces a single species of antibody, each with a unique antigen-binding site. When a naïve or memory B cell is activated by antigen (with the aid of a helper T cell), it proliferates and differentiates into an antibody-secreting effector cell.
Detailed explanation-4: -B cells are activated when they encounter an antigen that they recognize. The antigen binds to the B cell’s surface receptors, which activates and triggers it to divide and differentiate into an antibody-secreting plasma cell. Plasma cells produce antibodies that bind to the antigen and neutralize it.