AP BIOLOGY

THE HUMAN IMMUNE SYSTEM

IMMUNE RESPONSE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
When a macrophage engulfs a pathogen and displays the antigens, what happens next?
A
Helper T cells pick up information about the specific pathogen
B
B cells produce antibodies
C
Killer T cells destroy more pathogens
D
Nothing
Explanation: 

Detailed explanation-1: -Once stimulated by the appropriate antigen, helper T cells secrete chemical messengers called cytokines, which stimulate the differentiation of B cells into plasma cells (antibody-producing cells).

Detailed explanation-2: -Helper T cells become activated by interacting with antigen-presenting cells, such as macrophages. Antigen-presenting cells ingest a microbe, partially degrade it, and export fragments of the microbe-i.e., antigens-to the cell surface, where they are presented in association with class II MHC molecules.

Detailed explanation-3: -After binding to the antigen and MHC class II molecule presented by the dendritic cell, the naïve helper T cell becomes activated and proliferates. Instead of gaining the ability to kill infected cells, helper T cells acquire the ability to activate cells that bear MHC class II molecules.

Detailed explanation-4: -Phagocytosis: Once a macrophage engulfs a virus (1-3), it’s broken down with enzymes from the lysosomes (4, 5) then released from the cell as harmless waste material (6).

There is 1 question to complete.