AP BIOLOGY

Detailed explanation-1: -Group O plasma-rich blood components such as fresh frozen plasma (FFP) or platelet concentrates should not be given to patients of group A, B or AB if ABO-compatible components are readily available (Table 2.2).

Detailed explanation-2: -Plasma compatibility If you require plasma you should only receive plasma that doesn’t contain an antibody which could attack the antigens on your own red cells. Group A patients have A antigen on their red cells, so they can’t receive group O or group B plasma as the anti-A will attack their red cells.

Detailed explanation-3: -A person with type A blood receiving a transfusion of type B or AB blood would have an ABO incompatibility reaction. In an ABO incompatibility reaction, your immune system attacks the new blood cells and destroys them.

Detailed explanation-4: -For example, a patient with blood group A can receive blood from a donor with blood group A (which lacks the B antigen) or blood group O (which lacks all ABO blood group antigens). However, they cannot receive blood from a donor with blood group B or AB (which both have the B antigen).