THE HUMAN IMMUNE SYSTEM
TRANSFUSION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Epoetin alfa
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Epoet beta
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darbepoietin alfa
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Erythropoietin
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Detailed explanation-1: -In the United States, epoetin alfa (EPO) is the predominant ESA used by large dialysis chains, whereas the more recently approved longer-acting ESA, darbepoetin alfa (DPO), is mainly used in independent and hospital-based dialysis units.
Detailed explanation-2: -Compared with endogenous erythropoietin and epoetin alfa (rHuEPO), darbepoetin alfa has the characteristics of a prolonged half-life in the blood and increased biological activity in vivo.
Detailed explanation-3: -Epoetin, a synthetic form of the natural erythropoietin hormone, is used to treat dogs and cats with anemia caused by chronic kidney disease. The FDA (U.S. Food & Drug Administration) has approved this drug for use in humans but it is not officially approved for use in animals.
Detailed explanation-4: -Epoetin alfa (EPO) and darbepoetin alfa (DPO) are erythropoiesis-stimulating agents that are widely and interchangeably used for the treatment of anemia in patients with chronic kidney disease including those with end-stage renal disease requiring dialysis.