THE HUMAN IMMUNE SYSTEM
TRANSFUSION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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From the following list, which drugs are known to have epigenetic activity?
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azacitidine
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IDH1 and IDH2 inhibitor
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romidepsine
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depakine
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quinine
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Explanation:
Detailed explanation-1: -One example of an epigenetic change is DNA methylation-the addition of a methyl group, or a “chemical cap, ” to part of the DNA molecule, which prevents certain genes from being expressed. Another example is histone modification.
Detailed explanation-2: -Epigenetic drugs belong to a category of drugs used for treatment of specific cancers. These drugs fall into two groups: DNA methylation inhibitors and histone deacetylase inhibitors. FDA has approved seven drugs for cancer treatment.
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