AP BIOLOGY

Detailed explanation-1: -FFP and cryo can be used to treat a number of different conditions and diseases where clotting is a problem. For example, they can be given alongside red cells and platelets when patients have lost a large amount of blood or have problems with the way their blood is clotting.

Detailed explanation-2: -Although cryoprecipitate contains a higher concentration of fibrinogen than FFP, usually around 15 g/L, it shares many of the disadvantages of FFP (see Table I) as its fibrinogen concentration is not standardised and blood group matching is needed prior to transfusion.

Detailed explanation-3: -Cryopoor (Cryoprecipitate-poor) Plasma Cryoprecipitate-poor Plasma contains all coagulation factors except von Willebrand’s factor and factor VIII. Therefore, it can be used in the treatment of rodenticide toxicity as well as the replacement of proteins (albumin and immunoglobulins).

Detailed explanation-4: -During such medical circumstances, fresh frozen plasma (FFP) is clinically used for the reversal of excess warfarin-associated anticoagulation, as it contains all the coagulation factors that can alleviate the abnormal blood anticoagulation status in such patients.