THE HUMAN IMMUNE SYSTEM
TRANSFUSION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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in honor of Jacques Chirac?
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in honor of Jack Lang?
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Janus kinase
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Just another kinase
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Detailed explanation-1: -Fig. 2. a The Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway. JAKs are activated upon cytokine stimulation and phosphorylate STATs which results in dimerization and translocation of STATs to the nucleus in order to activate or suppress the transcription of genes.
Detailed explanation-2: -JAK inhibitors are a new class of arthritis drugs that treat rheumatoid arthritis. They’re not biologics. They are known as small molecule medications. JAK inhibitors come in pill form.
Detailed explanation-3: -Janus kinase (JAK) inhibitors are synthetic small molecule drugs that inhibit the activity and response of enzymes known as Janus kinases, and their signaling pathways.
Detailed explanation-4: -Janus kinases (JAKs) are a family of four enzymes; JAK1, JAK2, JAK3 and tyrosine kinase 2 (TYK2). They are essential for cytokine signalling and are strongly linked to both cancer and inflammatory diseases.