THE HUMAN IMMUNE SYSTEM
TYPES OF IMMUNITY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Prothrombin is converted into thrombin which acts on fibrinogen
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Prothrombin is converted into thrombin which acts on fibrin
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Fibrinogen is converted into fibrin which acts on prothrombin
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Fibrinogen is converted into fibrin which acts on thrombin
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Detailed explanation-1: -Prothrombin is transformed into thrombin by a clotting factor known as factor X or prothrombinase; thrombin then acts to transform fibrinogen, also present in plasma, into fibrin, which, in combination with platelets from the blood, forms a clot (a process called coagulation).
Detailed explanation-2: -Thrombin converts fibrinogen, a blood clotting factor that is normally dissolved in blood, into long strands of fibrin that radiate from the clumped platelets and form a net that entraps more platelets and blood cells.
Detailed explanation-3: -The common pathway is initiated via the activation of Factor Xa. Factor Xa combines with Factor Va and calcium on phospholipid surfaces to create a prothrombinase complex ultimately activating prothrombin (aka Factor II) into thrombin. This activation of thrombin occurs via serine protease cleaving of prothrombin.
Detailed explanation-4: -Activated thrombin leads to cleavage of fibrinogen into fibrin monomers that, upon polymerization, form a fibrin clot.
Detailed explanation-5: -Blood-clotting proteins generate thrombin, an enzyme that converts fibrinogen to fibrin, and a reaction that leads to the formation of a fibrin clot. … tissues outside the vessel stimulates thrombin production by the activation of the clotting system. Thrombin causes platelet aggregation.