AP BIOLOGY

THE HUMAN IMMUNE SYSTEM

TYPES OF IMMUNITY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which ion acts as a cofactor for thromboplastin
A
Ca2+
B
Fe2+
C
Mg2+
D
PO4-
Explanation: 

Detailed explanation-1: -Calcium ions (Ca2+) play a major role in the tight regulation of coagulation cascade that is paramount in the maintenance of hemostasis1, 2. Other than platelet activation, calcium ions are responsible for complete activation of several coagulation factors, including coagulation Factor XIII (FXIII)3.

Detailed explanation-2: -Clotting factor IV is a calcium ion that plays an important role in all 3 pathways. Some of the clotting factors function as serine proteases, specifically factors II, VI, IX, and X.

Detailed explanation-3: -Calcium is an element essential in various bodily functions such as neurotransmission, muscle contraction, and blood coagulation. It works with other clotting factors by acting as a cofactor and is involved in both extrinsic and intrinsic pathways.

Detailed explanation-4: -Thromboplastin (TPL) is derived from cell membranes and is a mixture of both phospholipids and tissue factor, neither of which are enzymes.

There is 1 question to complete.