THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The resulting protein translated from this sequence will be too short and will not function properly.
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The resulting protein translated from this sequence will be too long and will not function properly.
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There will be no effect. Mutations only matter if the mistake is in the tRNA sequence.
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There will be no effect. Mutations only matter if the mistake is in the DNA sequence.
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Detailed explanation-1: -A nonsense mutation occurs in DNA when a sequence change gives rise to a stop codon rather than a codon specifying an amino acid. The presence of the new stop codon results in the production of a shortened protein that is likely non-functional.
Detailed explanation-2: -Mutations can occur in noncoding regions of a gene and can affect the manner in which exons are removed from an mRNA product. If a mutation introduces a premature stop codon into an mRNA sequence, the: protein will be smaller.
Detailed explanation-3: -If there is a stop codon in the middle of an mRNA sequence then the protein will not be complete and may not be functional. A stop codon is a codon that signals that the translation of a protein is complete and causes the ribosome to release the mRNA.
Detailed explanation-4: -Consequently, once it encounters the mutation, the ribosome will read the mRNA sequence differently, which can result in the production of an entirely different sequence of amino acids in the growing polypeptide chain.
Detailed explanation-5: -An insertion changes the DNA sequence by adding one or more nucleotides to the gene.