THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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the mRNA will be changed from UAC to UAG
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The tRNA will be changed from UAC to TAC
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the mRNA will be changed from TUC to TUG
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the tRNA will be changed from CAU to CAC
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Detailed explanation-1: -Answer. Answer: C. The mRNA will be changed from U-A-C to U-A-G during transcription.
Detailed explanation-2: -mRNA strand is complementary to template strand of DNA, while coding strand has same sequence as RNA (except thymine at the place of uracil). Hence, the sequence of bases in mRNA will be AUUCGAUG.
Detailed explanation-3: -The codon for Methionine; the translation initiation codon. Usually, protein translation can only start at a Methionine codon (although this codon may be found elsewhere within the protein sequence as well). In eukaryotic DNA, the sequence is ATG; in RNA it is AUG.
Detailed explanation-4: -Consequently, once it encounters the mutation, the ribosome will read the mRNA sequence differently, which can result in the production of an entirely different sequence of amino acids in the growing polypeptide chain.
Detailed explanation-5: -Alteration of the sequence of bases in DNA can alter the structure of proteins. Sections of DNA which function as genes are transcribed into ‘pre-mRNA’, then edited and spliced to form mature messenger RNA (mRNA).