THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
The amino acid sequence would be shorter.
|
|
|
The identity of one amino acid would change.
|
|
|
The amino acid sequence would remain unchanged.
|
|
|
The identities of all amino acids would change.
|
Detailed explanation-1: -If AGCUCGAGU was mutated to ACCUCGAGU what would happen? The amino acid sequence would be shorter.
Detailed explanation-2: -Amino acid replacement is a change from one amino acid to a different amino acid in a protein due to point mutation in the corresponding DNA sequence. It is caused by nonsynonymous missense mutation which changes the codon sequence to code other amino acid instead of the original.
Detailed explanation-3: -Even changing just one amino acid in a protein’s sequence can affect the protein’s overall structure and function. For instance, a single amino acid change is associated with sickle cell anemia, an inherited disease that affects red blood cells.
Detailed explanation-4: -A change in a single amino acid in one of the hemoglobin proteins is responsible for causing the abnormal sickle shape of this red blood cell.
Detailed explanation-5: -If the change is to a similar amino acid or in a non-critical amino acid, the mutation protein may continue to function. However, if the amino acid is changed to a different type of amino acid or removes a critical amino acid (in terms of structure or activity), then the mutant protein may change in activity.