AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA MAKES RNA MAKES PROTEIN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which base pairings normally occur during DNA replication?
A
Guanine pairs with cytosine. Thymine pairs with thymine.
B
Thymine pairs with guanine. Cytosine pairs with adenine.
C
Cytosine pairs with cytosine. Thymine pairs with thymine.
D
Adenine pairs with thymine. Cytosine pairs with guanine.
Explanation: 

Detailed explanation-1: -Under normal circumstances, the nitrogen-containing bases adenine (A) and thymine (T) pair together, and cytosine (C) and guanine (G) pair together. The binding of these base pairs forms the structure of DNA .

Detailed explanation-2: -Replication relies on complementary base pairing, that is the principle explained by Chargaff’s rules: adenine (A) always bonds with thymine (T) and cytosine (C) always bonds with guanine (G).

Detailed explanation-3: -A unit of two bases in a molecule of DNA or RNA. In DNA, adenine always pairs with thymine (A-T), and guanine always pairs with cytosine (G-C). RNA is the same, except that adenine always pairs with uracil (A-U).

Detailed explanation-4: -Base pairs are found in double-stranded DNA and RNA, where the bonds between them connect the two strands, making the double-stranded structures possible. Base pairs themselves are formed from bases, which are complementary nitrogen-rich organic compounds known as purines or pyrimidines.

Detailed explanation-5: -Adenine always binds to thymine, while cytosine and guanine always bind to one another. This relationship is called complementary base paring. These complementary bases are bonded together via hydrogen bonds, which can be easily broken apart when the DNA needs to unzip and duplicate itself.

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