AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA MAKES RNA MAKES PROTEIN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following events in translation is the first to occur in eukaryotes?
A
elongation of the polypeptide
B
base pairing of activated methionine-tRNA to AUG of the messenger RNA
C
binding of the larger ribosomal subunit to smaller ribosomal subunits
D
the small subunit of the ribosome recognizing and attaching to the 5’cap
Explanation: 

Detailed explanation-1: -Which of the following events in translation is the first to occur in eukaryotes? When the ribosome reaches a stop codon on the mRNA, no corresponding tRNA enters the A site.

Detailed explanation-2: -Translation is generally divided into three stages: initiation, elongation, and termination (Figure 7.8). In both prokaryotes and eukaryotes the first step of the initiation stage is the binding of a specific initiator methionyl tRNA and the mRNA to the small ribosomal subunit.

Detailed explanation-3: -In this situation, translation begins at the 5’ end of the mRNA while the 3’ end is still attached to DNA. In all types of cells, the ribosome is composed of two subunits: the large (50S) subunit and the small (30S) subunit (S, for svedberg unit, is a measure of sedimentation velocity and, therefore, mass).

Detailed explanation-4: -Posted June 22, 2020. The 5’ cap protests the newly-synthesized mRNA from degradation. It also assists in ribosome binding to help initiating translation. 3’ poly-A tail protects mRNA from degradation, aids in exporting the mature mRNA to the cytoplasm, and is also involved in binding proteins to initiate translation.

Detailed explanation-5: -Initiation ("beginning"): in this stage, the ribosome gets together with the mRNA and the first tRNA so translation can begin.

There is 1 question to complete.