THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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It ‘unzips’ the DNA molecule
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It fuses the gaps in the sugar-phosphate backbone after the new strands of DNA have been made
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It adds new nucleotides to the old strands of DNA after it gets ‘unzipped.’
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It lays down a primer made of RNA for the DNA polymerase to attach to.
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Detailed explanation-1: -DNA ligases play an essential role in maintaining genomic integrity by joining breaks in the phosphodiester backbone of DNA that occur during replication and recombination, and as a consequence of DNA damage and its repair.
Detailed explanation-2: -During DNA replication, It attaches the Okazaki fragments formed from the lagging strand during the replication of DNA. It is the enzymes that are commonly used in genetic engineering. Complete answer: DNA ligase is a biochemical catalyst which is used to join two strands of DNA mostly during the DNA synthesis.
Detailed explanation-3: -The role of DNA ligase in DNA replication is to join the Okazaki fragments synthesized on the lagging strand into a continuous strand. In the case of leading strand, the nucleotides are added to the growing 3’ end continuously.