THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Is an enzyme
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Adds new nucleotides to the template strand
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Proofreads DNA strands to see that they are correct
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All of these are functions of DNA polymerase
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Detailed explanation-1: -The primary role of DNA polymerases is to accurately and efficiently replicate the genome in order to ensure the maintenance of the genetic information and its faithful transmission through generations.
Detailed explanation-2: -The synthesis of complementary pairs is the function of DNA polymerase-III.
Detailed explanation-3: -DNA Polymerase V (Pol V) is a polymerase enzyme involved in DNA repair mechanisms in bacteria, such as Escherichia coli. It is composed of a UmuD’ homodimer and a UmuC monomer, forming the UmuD’2C protein complex.
Detailed explanation-4: -The main function of the third polymerase, Pol III, is duplication of the chromosomal DNA, while other DNA polymerases are involved mostly in DNA repair and translesion DNA synthesis. Together with a DNA helicase and a primase, Pol III HE participates in the replicative apparatus that acts at the replication fork.
Detailed explanation-5: -DNA polymerase IV (pol IV) is one of three specialised DNA polymerases called into action during the SOS response to help cells tolerate certain types of DNA damage. The canonical view in the field is that pol IV primarily acts at replisomes that have stalled on the damaged DNA template.