THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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unzips & unwinds the DNA Helix, to start Replication.
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adds new nucleotides to make new DNA.
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bonds/glues new nucleotides together to finish Replication.
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Detailed explanation-1: -In DNA replication, ligase’s job is to join together fragments of newly synthesized DNA to form a seamless strand. The ligases used in DNA cloning do basically the same thing. If two pieces of DNA have matching ends, DNA ligase can join them together to make an unbroken molecule.
Detailed explanation-2: -To protect us from these dangers, our cells use DNA ligases to glue together DNA strands that have been broken.
Detailed explanation-3: -If the enzymatic molecule of DNA ligase is mutated and it becomes non-functional, the single strands of the replicated as well the newly synthesized DNA would not be joint, and by the end of the replication mechanism, DNA fragments will be present instead of proper DNA structure.
Detailed explanation-4: -DNA ligases are enzymes required for the repair, replication and recombination of DNA. DNA ligases catalyse the formation of phosphodiester bonds at single-strand breaks in double-stranded DNA.