THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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increases the number of nucleotides that can be polymerized per enzymatic cycle.
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holds open the two strands of the DNA molecule for access to the bond
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allows it to jump from one DNA strand to another.
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temporarily holds the nucleotides together until phosphodiester bonds can form.
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Detailed explanation-1: -The DNA polymerase is physically linked to clamp through a clamp-interacting sequence motif. This interaction serves to increase the processivity of DNA polymerase.
Detailed explanation-2: -The primary role of DNA polymerases is to accurately and efficiently replicate the genome in order to ensure the maintenance of the genetic information and its faithful transmission through generations.
Detailed explanation-3: -The polymerase catalyzes formation of a phosphodiester bond with the new deoxynucleotide, and then it effectively moves forward so that the next deoxynucleotide on the template can direct binding of the next deoxynucleoside triphosphate to the active site. During elongation, the new DNA strand is also the primer.
Detailed explanation-4: -“DNA Polymerases are a group of enzymes that catalyse the synthesis of DNA during replication.” The main function of DNA polymerases is to duplicate the DNA content of a cell during cell division. They do so by adding nucleotides at 3’-OH group of the growing DNA strand.