THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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holds DNA polymerase in place during strand extension
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extends the leading strand
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catalyzes the synthesis of the RNA primer, and provides a starting point of RNA or DNA polymerase to begin synthesis of new strand
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none of the above
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Detailed explanation-1: -Primase: synthesize the RNA primers required for initiating leading and lagging strand synthesis.
Detailed explanation-2: -Primase catalyzes the synthesis of a short RNA (or DNA in some living organisms) segment called a primer complementary to a ssDNA (single-stranded DNA) template.
Detailed explanation-3: -These primers serve as a starting point for DNA synthesis. Since primase produces RNA molecules, the enzyme is a type of RNA polymerase. Primase functions by synthesizing short RNA sequences that are complementary to a single-stranded piece of DNA, which serves as its template.
Detailed explanation-4: -The primase generates short strands of RNA that bind to the single-stranded DNA to initiate DNA synthesis by the DNA polymerase. This enzyme can work only in the 5’ to 3’ direction, so it replicates the leading strand continuously.