THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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RNA Primase
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DNA Primase
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DNA Ligase
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Helicase
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Detailed explanation-1: -DNA ligase is the enzyme that binds adjacent Okazaki fragments on the lagging strand, resulting in a continuous daughter strand where DNA polymerase had worked in a discontinuous fashion.
Detailed explanation-2: -There is compelling evidence that DNA ligase I is predominantly responsible for joining Okazaki fragments generated by discontinuous DNA synthesis on the lagging strand at the replication fork.
Detailed explanation-3: -Okazaki segments are joined by DNA ligase.
Detailed explanation-4: -Enzyme ligase connects (ligates) the two Okazaki fragments into one continuous newly synthesized complementary strand. DNA ligase I-DNA ligase I connects the Okazaki fragments during the synthesis. Hence, the correct option is option C, ‘Ligase’.