AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA REPLICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
This specialized enzyme will connect Okazaki Segments that have been created on the Lagging strand.
A
RNA Primase
B
DNA Primase
C
DNA Ligase
D
Helicase
Explanation: 

Detailed explanation-1: -DNA ligase is the enzyme that binds adjacent Okazaki fragments on the lagging strand, resulting in a continuous daughter strand where DNA polymerase had worked in a discontinuous fashion.

Detailed explanation-2: -There is compelling evidence that DNA ligase I is predominantly responsible for joining Okazaki fragments generated by discontinuous DNA synthesis on the lagging strand at the replication fork.

Detailed explanation-3: -Okazaki segments are joined by DNA ligase.

Detailed explanation-4: -Enzyme ligase connects (ligates) the two Okazaki fragments into one continuous newly synthesized complementary strand. DNA ligase I-DNA ligase I connects the Okazaki fragments during the synthesis. Hence, the correct option is option C, ‘Ligase’.

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