AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA REPLICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the complementary strand of:3’ ACCGTCGAT 5’?
A
5’ TGGCAGCTA 3’
B
5’ UGGCAGCUA 3’
C
3’ TGGCAGCTA 5’
D
3’ UGGCAGCUA 5’
Explanation: 

Detailed explanation-1: -The if given the base sequence for one strand: 5’-AGGTCCG-3’, the complimentary strand must have the sequence: 3’-TCCAGGC-5’.

Detailed explanation-2: -The correct option is C The complementary DNA strand of the sequence ATGC will be TACG. The complementary base pairing in DNA is as per the Chargaff’s rules. According to these rules, purines always hydrogen bond with pyrimidines and vice-versa. Thus, adenine always hydrogen bonds with thymine by two hydrogen bonds.

Detailed explanation-3: -The DNA strands have the opposite orientation: one strand is in the 5′ to 3′ direction with respect to the carbon atoms on the sugar (deoxyribose) and the complementary strand is in the 3′ to 5′ direction (Figure 1(a)).

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