AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA REPLICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
When does replication occur?
A
G0 phase
B
G1 phase
C
G2 phase
D
S phase
Explanation: 

Detailed explanation-1: -The S phase of a cell cycle occurs during interphase, before mitosis or meiosis, and is responsible for the synthesis or replication of DNA. In this way, the genetic material of a cell is doubled before it enters mitosis or meiosis, allowing there to be enough DNA to be split into daughter cells.

Detailed explanation-2: -The division cycle of most eukaryotic cells is divided into four discrete phases: M, G1, S, and G2. M phase (mitosis) is usually followed by cytokinesis. S phase is the period during which DNA replication occurs.

Detailed explanation-3: -S phase is the period of wholesale DNA synthesis during which the cell replicates its genetic content; a normal diploid somatic cell with a 2N complement of DNA at the beginning of S phase acquires a 4N complement of DNA at its end.

Detailed explanation-4: -DNA replicates in the S phase of the cell cycle and initiates at specific regions in the DNA sequence known as DNA replication ‘origins’. A number of proteins participate in DNA replication and the process is subject to scrutiny by cell surveillance mechanisms called cell cycle checkpoints.

Detailed explanation-5: -S phase. In S phase, the cell synthesizes a complete copy of the DNA in its nucleus. It also duplicates a microtubule-organizing structure called the centrosome. The centrosomes help separate DNA during M phase.

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