THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which of the following is the second step in DNA replication?
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Helicase breaks the hydrogen bonds between the bases to split the original strand.
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Primase marks where to start building the new strand of DNA
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DNA Polymerase starts to attach new nucleotides to the original strand
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There are fragments left on the lagging strand when DNA polymerase is done
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Ligase glues together the fragments on the lagging strand of DNA
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Explanation:
Detailed explanation-1: -Once the DNA strands have been separated, a short piece of RNA called a primer binds to the 3’ end of the strand. The primer always binds as the starting point for replication. Primers are generated by the enzyme DNA primase.
Detailed explanation-2: -Special proteins are responsible for loading primase at the origin of replication so that leading strand DNA synthesis can commence. In a subsequent step, other replication proteins cause primase to initiate DNA replication on the opposite lagging strand.
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