AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA REPLICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following is true regarding these DNA repair mechanisms?
A
DNA damage from chemical reactions cannot be undone.
B
Proofreading from DNA polymerase reduces the error rate in DNA to about 1 in 100 nucleotides.
C
Copying errors not caught by the replication machinery can be corrected by mismatch repair
D
Non-homologous end joining is less likely to produce mutations than homologous recombination.
Explanation: 

Detailed explanation-1: -The true statement about DNA repair is that they can recognize double helix distortions. Thank you for taking the time to thank me. The answer is option C.

Detailed explanation-2: -Immediately after DNA synthesis, any remaining mispaired bases can be detected and replaced in a process called mismatch repair. If DNA gets damaged, it can be repaired by various mechanisms, including chemical reversal, excision repair, and double-stranded break repair.

Detailed explanation-3: -Answer and Explanation: If DNA replication goes wrong, the cell can either repair the mistakes or go through apoptosis. During DNA replication, DNA polymerase occasionally makes errors in inserting nucleotides into the growing strand. This can be corrected by DNA polymerase itself or other DNA repair enzymes.

Detailed explanation-4: -The DNA mismatch repair system is a bidirectional excision-resynthesis system that is initiated at a defined strand scission that is 3′-or 5′-of a mismatch and the excision tract extends to a nonspecific point just past the mismatch [12, 13].

Detailed explanation-5: -Answer and Explanation: The correct answer is C. Photoreactivation repair.

There is 1 question to complete.