THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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DNA polymerase synthesizes a complementary strand from one, but not both, of the original strands.
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DNA polymerase synthesizes a complementary strand from each of the original strands.
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DNA ligase breaks apart one of the original strands, and other enzymes re-assemble the components into a new strand.
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DNA ligase breaks apart both of the original strands, and other enzymes re-assemble the components into two new strands.
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Detailed explanation-1: -Each end of the bubble is a replication fork, a Y-shaped junction where double-stranded DNA is separated into two single strands. New DNA complementary to each single strand is synthesized at each replication fork.
Detailed explanation-2: -Replication relies on complementary base pairing, that is the principle explained by Chargaff’s rules: adenine (A) always bonds with thymine (T) and cytosine (C) always bonds with guanine (G).
Detailed explanation-3: -DNA replication initiates at specific points, called origins, where the DNA double helix is unwound. A short segment of RNA, called a primer, is then synthesized and acts as a starting point for new DNA synthesis. An enzyme called DNA polymerase next begins replicating the DNA by matching bases to the original strand.
Detailed explanation-4: -Replication occurs in three major steps: the opening of the double helix and separation of the DNA strands, the priming of the template strand, and the assembly of the new DNA segment.