THE MOLECULAR BASIS OF INHERITANCE
GENE MUTATION
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Deletion of one nucleotide
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Alteration of the start codon
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Insertion of one nucleotide
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Substitution of one nucleotide
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Detailed explanation-1: -Silent mutation: Some mutations that change DNA bases do not have any effect on the sequence of amino acids in the protein. These mutations are called silent mutations and they do not affect the structure or function of the protein because there is no effect on the amino acid sequence.
Detailed explanation-2: -Answer. It could be a silent mutation which means it happened in the non coding part of thegene and this is why it did not affect the phenotype. It could also be a substitutionmutation but the new code that was developed codes for the same amino acid, and this is why the protein did not change.
Detailed explanation-3: -Silent mutations occur when the change of a single DNA nucleotide within a protein-coding portion of a gene does not affect the sequence of amino acids that make up the gene’s protein.
Detailed explanation-4: -Even though an nucleotide sequence is changed, it does not alter the amino acid of the polypeptide, this is because silent mutation only occurs in the third base of codons as genetic code is degenerate. As silent mutations do not affect the function of the protein, it is considered as a neutral mutation.