THE MOLECULAR BASIS OF INHERITANCE
GENE MUTATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Base Substitution
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Base Deletion
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Base Insertion
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Detailed explanation-1: -Definition. A deletion, as related to genomics, is a type of mutation that involves the loss of one or more nucleotides from a segment of DNA. A deletion can involve the loss of any number of nucleotides, from a single nucleotide to an entire piece of a chromosome.
Detailed explanation-2: -Mutations can be of many types, such as substitution, deletion, insertion, and translocation.
Detailed explanation-3: -The HTT mutation that causes Huntington disease involves a DNA segment known as a CAG trinucleotide repeat . This segment is made up of a series of three DNA building blocks (cytosine, adenine, and guanine) that appear multiple times in a row. Normally, the CAG segment is repeated 10 to 35 times within the gene.
Detailed explanation-4: -Types of Mutations There are three types of DNA Mutations: base substitutions, deletions and insertions.