AP BIOLOGY

Detailed explanation-1: -Nonsense: A nonsense variant is another type of substitution. Instead of causing a change in one amino acid, however, the altered DNA sequence results in a stop signal that prematurely signals the cell to stop building a protein.

Detailed explanation-2: -Substitution mutations just switch out one or more bases for different ones. Substitution mutations can cause many kinds of mutations. Some of these include nonsense, missense, and silent mutations. All of these depend on whether or not the new base codes for an amino acid different than the original.

Detailed explanation-3: -Missense codons (missense mutations): A change in a single amino acid that results from a point mutation in the DNA sequence. Nonsense codons (nonsense mutations): The conversion of a codon from one that encodes an amino acid to one that acts as a stop codon due to a point mutation in the DNA sequence.

Detailed explanation-4: -A nonsense mutation, or its synonym, a stop mutation, is a change in DNA that causes a protein to terminate or end its translation earlier than expected.