AP BIOLOGY

Detailed explanation-1: -Lethal mutations usually stem from lethal genes or alleles. Depending on the genes involved, fatal genes can be dominant, recessive, or even conditional. The death of an entity can occur at any moment, with the most prevalent occurrence being during the early phases of development.

Detailed explanation-2: -Frameshift mutations are generally much more serious and often more deadly than point mutations. Even though only a single nitrogen base is affected, as with point mutations, in this instance, the single base is either completely deleted or an extra one is inserted into the middle of the DNA sequence.

Detailed explanation-3: -Examples of human diseases caused by recessive lethal alleles include cystic fibrosis, sickle-cell anemia, and achondroplasia. Achondroplasia is an autosomal dominant bone disorder that causes dwarfism.

Detailed explanation-4: -Lethals or lethal genes or lethal alleles are alleles causing the end of an entity which carries it. Basically, lethal genes are lethal to the organism carrying it, lethal meaning (here) death. Typically it is the consequence of gene-mutation that is required to grow and develop.