AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

GENE MUTATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Hydroxylamine is a mutagen. It converts cytosine to a compound which pairs up with adenine. If DNA is treated with hydroxylamine, the mutation which results is an example of a base ____
A
deletion
B
insertion.
C
inversion.
D
substitution.
Explanation: 

Detailed explanation-1: -Oxylamines such as hydroxylamine and methoxylamine disturb DNA replication and act as potent mutagens, causing nucleotide transition from one purine to another or one pyrimidine to another.

Detailed explanation-2: -Hydroxylamine is a mutagen that leads to the transitions in the nucleotide, causing frameshift mutations.

Detailed explanation-3: -Hydroxylamine can induce any one of the four types of transition mutations in bacteriophage S13 if the mutagen is added directly to agar plates seeded with phage and bacterial indicators. The phage can also be mutated by treating the host cell with hydroxylamine before infecting it with phage.

Detailed explanation-4: -The four main types of structural chromosomal aberrations are deletion, duplication, inversion, and translocation.

There is 1 question to complete.