THE MOLECULAR BASIS OF INHERITANCE
GENE MUTATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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at most only two amino acids would change.
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at most only one amino acid would change.
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all the amino acids downstream of the mutation would change.
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there would be no effect.
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Detailed explanation-1: -The change can cause the wrong amino acid to be produced. In some cases, the change has little effect. In other cases, the incorrect amino acid can affect the structure or function of the protein being encoded.
Detailed explanation-2: -Changes to a gene’s DNA sequence, called mutations, can change the amino acid sequence of the protein it codes for-but they don’t always. A point mutation is a change to single DNA letter. They fall into three categories: Missense mutations cause a single amino acid change in the protein.
Detailed explanation-3: -A mutation in the amino acid sequence may alter the structure of a protein but it does not necessarily alter its function, although, the mutation at specific sites such as conserved residues can bring about a change in the structure and function of the protein.
Detailed explanation-4: -If the change is to a similar amino acid or in a non-critical amino acid, the mutation protein may continue to function. However, if the amino acid is changed to a different type of amino acid or removes a critical amino acid (in terms of structure or activity), then the mutant protein may change in activity.