AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

GENE MUTATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following is not an example of a point mutation?
A
Silent mutation
B
Nonsense mutation
C
Missense mutation
D
Frameshift mutation
Explanation: 

Detailed explanation-1: -Which of the following is not a point mutation? Explanation: Point mutation concerns a single base. Thus substitution, which includes transversion, and insertion or deletion, falls within point mutation. On the other hand, translocation involves a stretch of bases so it is not a point mutation.

Detailed explanation-2: -A frameshift mutation is an insertion or deletion of a nucleotide base that changes the reading frame. A point mutation does not change the frame and only changes one amino acids.

Detailed explanation-3: -No, point mutations and frameshift mutations are two different types of gene mutations that happen in the nucleotide sequence of a gene.

Detailed explanation-4: -Crohn’s disease, cystic fibrosis, and certain types of cancer are due to frameshift mutations.

Detailed explanation-5: -Types of Point Mutations. We are going to focus on the following point mutations: frameshift, silent, nonsense, and missense. Let’s start with a frameshift mutation, where there’s an insertion or deletion of one or more bases.

There is 1 question to complete.