THE MOLECULAR BASIS OF INHERITANCE
GENE MUTATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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A point mutation
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A silent mutation
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A frameshift mutation
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Detailed explanation-1: -Frameshift Mutation If a mutation disrupts this normal reading frame, then the entire gene sequence following the mutation will be incorrectly read. This can result in the addition of the wrong amino acids to the protein and/or the creation of a codon that stops the protein from growing longer.
Detailed explanation-2: -This occurs when one nucleotide base is substituted for another in a DNA sequence. The change can cause the wrong amino acid to be produced. In some cases, the change has little effect. In other cases, the incorrect amino acid can affect the structure or function of the protein being encoded.
Detailed explanation-3: -frameshift mutation because the change introduces an extra T near the beginning of the sequence. This will change the frame of the codons of the gene. The starting sequence of a gene changed from AUGTTCGACGTG to AUGTTTCGACGTG.
Detailed explanation-4: -A frameshift variant occurs when there is an addition or loss of nucleotides that shifts the grouping and changes the code for all downstream amino acids. The resulting protein is usually nonfunctional. Insertions, deletions, and duplications can all be frameshift variants.