AP BIOLOGY

Detailed explanation-1: -Mutational effects can be beneficial, harmful, or neutral, depending on their context or location. Most non-neutral mutations are deleterious. In general, the more base pairs that are affected by a mutation, the larger the effect of the mutation, and the larger the mutation’s probability of being deleterious.

Detailed explanation-2: -The majority of mutations are neutral in their effects on the organisms in which they occur. Beneficial mutations may become more common through natural selection. Harmful mutations may cause genetic disorders or cancer.

Detailed explanation-3: -Non-conservative mutations can be more severe because they cause a greater change to the protein sequence or expression level. An example would be changing an acidic amino acid into a basic one.

Detailed explanation-4: -Genetic mutations are changes to your DNA sequence that happen during cell division when your cells make copies of themselves. Your DNA tells your body how to form and function. Genetic mutations could lead to genetic conditions like cancer, or they could help humans better adapt to their environment over time.

Detailed explanation-5: -To their surprise, the researchers found that 75.9% of synonymous mutations were significantly deleterious, while 1.3% were significantly beneficial.