AP BIOLOGY

Detailed explanation-1: -A substitution mutation is a type of replication error during DNA replication which places the wrong nucleotide or sequence of nucleotides in the wrong position. A type of substitution mutation, a point mutation, occurs which a single nucleotide is substituted.

Detailed explanation-2: -Single base substitutions are called point mutations, recall the point mutation Glu—–> Val which causes sickle-cell disease. Point mutations are the most common type of mutation and there are two types.

Detailed explanation-3: -Substitution mutation is sometimes referred to as point mutation. However, point mutation is defined particularly as a type of mutation involving a change of only one nucleotide. See also: transversion.

Detailed explanation-4: -Point mutation, also known as substitution, is a type of genetic mutation where the nucleotide base is inserted, deleted, or changed in the DNA or RNA of the genome of an organism.

Detailed explanation-5: -A substitution is a mutation that exchanges one base for another (i.e., a change in a single “chemical letter” such as switching an A to a G). Such a substitution could: change a codon to one that encodes a different amino acid and cause a small change in the protein produced.