AP BIOLOGY

Detailed explanation-1: -Chargaff’s rules state that in the DNA of any species and any organism, the amount of guanine should be equal to the amount of cytosine and the amount of adenine should be equal to the amount of thymine. Further a 1:1 stoichiometric ratio of purine and pyrimidine bases (i.e., A+G=T+C ) should exist.

Detailed explanation-2: -Purine and pyrimidine bases should be present in a 1:1 ratio in the DNA of any organism. The base pair rule is another name for Chargaff’s rule. It specifies that the amounts of guanine and cytosine be the same. While the ratios of adenine and thiamine are the same.

Detailed explanation-3: -In 1950, biochemist Erwin Chargaff found that the arrangement of nitrogen bases in DNA varied widely, but the amount of certain bases always occurred in a one-to-one ratio.

Detailed explanation-4: -Rule 2. In 1947 Chargaff showed that the composition of DNA, in terms of the relative amounts of the A, C, G and T bases, varied from one species to another. This molecular diversity added evidence that DNA could be the genetic material.

Detailed explanation-5: -Chargaff’s rules state that DNA from any cell of all organisms should have a 1:1 ratio (base Pair Rule) of pyrimidine and purine bases and, more specifically, that the amount of guanine is equal to cytosine and the amount of adenine is equal to thymine.