THE MOLECULAR BASIS OF INHERITANCE
THE HUMAN GENOME
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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does not have the disorder but can pass it on to offspring.
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can develop the disorder later in life but cannot pass it on.
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has a dominant normal allele that has been inactivated.
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passes the disorder to offspring on the Y chromosome only.
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Detailed explanation-1: -A person with a single gene disorder has a 50/50 chance of passing the mutated allele to a child who will become a carrier. If both parents have a heterozygous recessive mutation, their children will have a one-in-four chance of developing the disorder. The risk will be the same for every birth.
Detailed explanation-2: -A person with one abnormal gene is called heterozygous for that gene. If a child receives an abnormal recessive disease gene from both parents, the child will show the disease and will be homozygous (or compound heterozygous) for that gene. GENETIC DISORDERS. Almost all diseases have a genetic component.
Detailed explanation-3: -Recessive inheritance means both genes in a pair must be abnormal to cause disease. People with only one defective gene in the pair are called carriers. These people are most often not affected with the condition. However, they can pass the abnormal gene to their children.
Detailed explanation-4: -In a heterozygous genotype, the dominant allele overrules the recessive one. Therefore, the dominant trait will be expressed. The recessive trait won’t show, but you’re still a carrier. This means you can pass it on to your children.