AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

THE HUMAN GENOME

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is DNA sequencing?
A
The total of genes carried by an individual or cellCoding genes in order to identify single nucleotide
B
polymorphisms
C
Deciphering the functions of various parts of the human genome
D
The process of identifying the order of the bases in DNA
Explanation: 

Detailed explanation-1: -DNA sequencing refers to the general laboratory technique for determining the exact sequence of nucleotides, or bases, in a DNA molecule. The sequence of the bases (often referred to by the first letters of their chemical names: A, T, C, and G) encodes the biological information that cells use to develop and operate.

Detailed explanation-2: -Sanger sequencing: The chain termination method Regions of DNA up to about 900 base pairs in length are routinely sequenced using a method called Sanger sequencing or the chain termination method. Sanger sequencing was developed by the British biochemist Fred Sanger and his colleagues in 1977.

Detailed explanation-3: -Determining the order of the nucleotides within a gene is known as DNA sequencing. The earliest DNA sequencing methods were time consuming, but a major breakthrough came in 1975 with the development of the process called Sanger sequencing.

Detailed explanation-4: -The four bases in DNA are adenine (A), cytosine (C), guanine (G), and thymine (T). These bases form specific pairs (A with T, and G with C). Base pair may also refer to the actual number of base pairs, such as 8 base pairs, in a sequence of nucleotides.

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