AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

THE HUMAN GENOME

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which chromosome in Human Genome has more genes?
A
Chromosome 1
B
Chromosome 2
C
Chromosome 3
Explanation: 

Detailed explanation-1: -Chromosome 1 is the largest human chromosome, spanning about 249 million DNA building blocks (base pairs) and representing approximately 8 percent of the total DNA in cells.

Detailed explanation-2: -Chromosome 1 is gene-dense, with 3, 141 genes and 991 pseudogenes, and many coding sequences overlap.

Detailed explanation-3: -Chromosomes are also different sizes. The human X chromosome is about three times larger than the human Y chromosome, containing about 900 genes, while the Y chromosome has about 55 genes. The unique structure of chromosomes keeps DNA tightly wound around spool-like proteins, called histones.

Detailed explanation-4: -DMD, the largest known human gene, provides instructions for making a protein called dystrophin. This protein is located primarily in muscles used for movement (skeletal muscles) and in heart (cardiac) muscle. Small amounts of dystrophin are present in nerve cells in the brain.

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