THE MOLECULAR BASIS OF INHERITANCE
THE SEARCH FOR INHERITABLE MATERIAL
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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It suggested that DNA is the transforming principle
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It confirmed that DNA is a double helix composed of two antiparallel strands
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It demonstrated that DNA consists of four nucleotides where the Proportions of adenine/thymine and cytosine/guanine remain constant
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It proved that DNA is semiconservatively replicated
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Detailed explanation-1: -Griffith used two strains of pneumococcus (Streptococcus pneumoniae) bacteria: a type III-S and a type II-R.
Detailed explanation-2: -Frederick Griffith performed experiments on Streptococcus pneumoniae which is responsible for causing pneumonia. He observed that the bacteria produce two colonies as: R strain: rough colonies which are non-virulent. S strain: smooth colonies which are virulent and caused the death of mice.
Detailed explanation-3: -Oswald Avery, Colin MacLeod, and Maclyn McCarty showed that DNA (not proteins) can transform the properties of cells, clarifying the chemical nature of genes. Avery, MacLeod and McCarty identified DNA as the “transforming principle” while studying Streptococcus pneumoniae, bacteria that can cause pneumonia.
Detailed explanation-4: -Griffith’s experiment, reported in 1928 by Frederick Griffith, was the first experiment suggesting that bacteria are capable of transferring genetic information through a process known as transformation.