AP BIOLOGY

LABORATORY REVIEW

MOLECULAR BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
HISTORY:Rosalind Franklin used x-ray crystallography to determine that the shape of the DNA molecule is:
A
a cloverleaf
B
a braided rope
C
a pleated sheet
D
a twisted ladder
Explanation: 

Detailed explanation-1: -Created by Rosalind Franklin using a technique called X-ray crystallography, it revealed the helical shape of the DNA molecule. Watson and Crick realized that DNA was made up of two chains of nucleotide pairs that encode the genetic information for all living things.

Detailed explanation-2: -The discovery of the structure of DNA in 1953 was made possible by Dr Rosalind Franklin’s X-ray diffraction work at King’s. Her creation of the famous Photo 51 demonstrated the double-helix structure of deoxyribonucleic acid: the molecule containing the genetic instructions for the development of all living organisms.

Detailed explanation-3: -At King’s College London, Rosalind Franklin obtained images of DNA using X-ray crystallography, an idea first broached by Maurice Wilkins. Franklin’s images allowed James Watson and Francis Crick to create their famous two-strand, or double-helix, model.

Detailed explanation-4: -Franklin used x-ray crystallography to investigate the physical chemistry of carbon and coal. Her findings enabled her to predict how different types of coal would perform as vital fuels for the war effort.

Detailed explanation-5: -Crystals are solids with regular, repeating units of atoms. Some biological macromolecules, such as DNA, can form fibers suitable for analysis using X-ray crystallography because their solid forms consist of atoms arranged in a regular pattern.

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