AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA REPLICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What does the enzyme DNA helicase do within a cell?
A
unzips the DNA by breaking hydrogen bonds
B
matches up base pairs
C
finds free floating nucleotides and brings them to DNA
D
it helps to break apart the backbone of DNA
Explanation: 

Detailed explanation-1: -DNA helicase continues to unwind the DNA forming a structure called the replication fork, which is named for the forked appearance of the two strands of DNA as they are unzipped apart. The process of breaking the hydrogen bonds between the nucleotide base pairs in double-stranded DNA requires energy.

Detailed explanation-2: -DNA helicases catalyze the disruption of the hydrogen bonds that hold the two strands of double-stranded DNA together. This energy-requiring unwinding reaction results in the formation of the single-stranded DNA required as a template or reaction intermediate in DNA replication, repair and recombination.

Detailed explanation-3: -DNA helicases are molecular motors. Through conformational changes caused by ATP hydrolysis and binding, they move along the template double helix, break the hydrogen bonds between the two strands and separate the template chains, so that the genetic information can be accessed.

Detailed explanation-4: -Key enzyme involved in DNA replication, it is responsible for ‘unzipping’ the double helix structure by breaking the hydrogen bonds between bases on opposite strands of the DNA molecule.

Detailed explanation-5: -The main function of DNA helicase is to separate two strands of DNA for replication. Helicase is the enzyme, which unzips the DNA strands by breaking the hydrogen bonds between them.

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