AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA REPLICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which is the third step?
A
DNA Helicase unwinds original DNA strand
B
RNA Primase lays down RNA primer for new nucleotide bases.
C
DNA polymerase builds new strands by bring in new nucleotide bases.
D
Ligase knits together fragments on lagging strand
Explanation: 

Detailed explanation-1: -DNA polymerase builds new strands by bring in new nucleotide bases. Which is the third step? RNA Primase lays down RNA primer for new nucleotide bases.

Detailed explanation-2: -Each strand in the double helix acts as a template for synthesis of a new, complementary strand. New DNA is made by enzymes called DNA polymerases, which require a template and a primer (starter) and synthesize DNA in the 5’ to 3’ direction.

Detailed explanation-3: -Elongation. During elongation, an enzyme called DNA polymerase adds DNA nucleotides to the 3′ end of the newly synthesized polynucleotide strand.

Detailed explanation-4: -Because DNA polymerase can only synthesize DNA in a 5′ to 3′ direction, the other new strand is put together in short pieces called Okazaki fragments. The Okazaki fragments each require a primer made of RNA to start the synthesis. The strand with the Okazaki fragments is known as the lagging strand.

Detailed explanation-5: -Step 3: Termination During termination, DNA replication comes to an end. An exonuclease enzyme removes the DNA primers and replaces them with DNA. DNA ligase fuses together the Okazaki fragments and telomerase adds telomeres to the ends of DNA.

There is 1 question to complete.