FOOD TECHNOLOGY

Detailed explanation-1: -Although later reviews of those experimental data and evaluation of additional data led scientists to conclude that cyclamate does not cause cancer, it has not been reapproved in the United States (although it is approved in many other countries).

Detailed explanation-2: -Additional considerations. Although sodium cyclamate is not considered to be harmful at levels of exposure considered in the assessment, this substance has health effects of concern based on its potential to cause reproductive effects.

Detailed explanation-3: -Cyclamate was discovered in 1937. It was used as a low-calorie sweetener in the United States in the 1950s and 1960s. It is a salt of cyclohexylsulfamic acid. Sodium cyclamate is used as an NNS, and the analogous calcium salt is used especially in low-sodium diets. Cyclamate is 30 times sweeter than sucrose.

Detailed explanation-4: -Cyclamates were approved as a sweetener in the United States in 1951. There was great interest in the new sweetener (before cyclamates there had only been saccharin). Cyclamates were not as sweet as saccharin, and it was more expensive to make, but it did not have the metallic aftertaste of saccharin.